Directeur.e(s) de recherche
Elsa Rousseau
Start date
Title of the research project
Study of bacterial-phage interactions in in vitro gut digestion systems
Description

Rose-Marie's project focuses on the analysis of interactions between bacteriophages - the viruses of bacteria - and bacteria of the intestinal microbiota based on datasets from experiments carried out by the student in collaboration with members of the Institute of Nutrition and Functional Foods (INAF) at Université Laval. The first objective is to study the impact of phages on bacterial dynamics in a simplified microbiota, composed of 8 key bacterial strains of the human intestinal microbiota. The second objective is to study the bacterial-phage dynamics in a complex microbiota representative of the human gut microbiota. For both objectives, following the experimentation and acquisition of sequencing data, Rose-Marie will perform data analysis using bioinformatics methods. This project could have important implications for the understanding of interactions between bacteria and phages, which are very poorly known, but also for the knowledge of the intestinal microbiota in relation to nutrition and health of individuals.

Discover

Featured project

Radiotherapy treatments currently used in the clinical field are rarely modified. They generally consist of a global therapy of 50 grays, fractionated in five treatments of two grays every week for five weeks.
Thus, it could be worthwhile to develop a numeric tool, based on mathematical models found in the literature, in order to compare different types of treatment without having to test them on real tissues. Several parameters are known to alter the tissue response after irradiation including oxygen

Read more