Directeur.e(s) de recherche
Elsa Rousseau
Start date
Title of the research project
Study of bacterial-phage interactions in in vitro gut digestion systems
Description

Rose-Marie's project focuses on the analysis of interactions between bacteriophages - the viruses of bacteria - and bacteria of the intestinal microbiota based on datasets from experiments carried out by the student in collaboration with members of the Institute of Nutrition and Functional Foods (INAF) at Université Laval. The first objective is to study the impact of phages on bacterial dynamics in a simplified microbiota, composed of 8 key bacterial strains of the human intestinal microbiota. The second objective is to study the bacterial-phage dynamics in a complex microbiota representative of the human gut microbiota. For both objectives, following the experimentation and acquisition of sequencing data, Rose-Marie will perform data analysis using bioinformatics methods. This project could have important implications for the understanding of interactions between bacteria and phages, which are very poorly known, but also for the knowledge of the intestinal microbiota in relation to nutrition and health of individuals.

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